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[db-085] 1P103 : NADPH-diaphorase陽性三叉神経吻側亜核-孤束核複合体ニューロンでのペプチド



##Begin
#Z 1P103
#A NADPH-diaphorase陽性三叉神経吻側亜核-孤束核複合体ニューロンでのペプチド
の共存
#B Colocalization of peptides with NADPH-diaphorase-positive neurons in t
rigemino-solitary complex.
#E1 竹村/元秀
#F1 たけむら/もとひで
#G1 Takemura/Motohide
#J1 大阪大学歯学部口腔解剖学第二講座
#K1 おおさか だいがく しがくぶ こうくう かいぼうがく だいに こうざ
#L1 The Second Department of Oral Anatomy, Osaka University Faculty of Den
tistry
#E2 脇坂/聡
#F2 わきさか/さとし
#G2 Wakisaka/Satoshi
#J2 大阪大学歯学部口腔解剖学第一講座
#K2 おおさか だいがく しがくぶ こうくう かいぼうがく だいいち こうざ
#L2 The First Department of Oral Anatomy, Osaka University Faculty of Dent
istry
#E3 島田/豊美
#F3 しまだ/とよみ
#G3 Shimada/Toyomi
#J3 大阪大学歯学部口腔解剖学第二講座
#K3 おおさか だいがく しがくぶ こうくう かいぼうがく だいに こうざ
#L3 The Second Department of Oral Anatomy, Osaka University Faculty of Den
tistry
#E4 岩瀬/勝也
#F4 いわせ/かつや
#G4 Iwase/Katsuya
#J4 大阪大学歯学部歯科補綴学第二講座
#K4 おおさか だいがく しがくぶ しかほてつがく だいに こうざ
#L4 The Second Department of Prosthetic Dentistry, Osaka University Facult
y of Dentistry
#E5 辻尾/篤俊
#F5 つじお/あつとし
#G5 Tsujio/Atsutoshi
#J5 大阪大学歯学部歯科補綴学第二講座
#K5 おおさか だいがく しがくぶ しかほてつがく だいに こうざ
#L5 The Second Department of Prosthetic Dentistry, Osaka University Facult
y of Dentistry
#E6 重永/凱男
#F6 しげなが/よしお
#G6 Shigenaga/Yoshio
#J6 大阪大学歯学部口腔解剖学第二講座
#K6 おおさか だいがく しがくぶ こうくう かいぼうがく だいに こうざ
#L6 The Second Department of Oral Anatomy, Osaka University Faculty of Den
tistry
#D
#M 一酸化窒素, 三叉神経核,孤束核,NADPH-diaphorase,神経ペプチド,カルシ
ウム結合蛋白
#N nitric oxide,trigeminal nuclei,solitary nucleus, NADPH-diaphorase ,neur
opeptide ,calcium binding protein
#T We double-labeled NADPH-d histochemically and central terminal area of
branches mandibular nerve and chorda tympani using transganglionic
transport of WGA-HRP. The NADPH-d-positive neurons (NADPH-d neuron)
composed a sparse network in the dorsomedial spinal trigeminal nucleus
oralis (Vo) and a dense one in the rostrolateral solitary tract nucleus
(Sn). On the other hand in the nucleus interpolaris (Vi) and caudalis (Vc),
scattered population of labeled neurons were in the paratrigeminal nucleus
(paraV) and the gap area between Vi and Vc. In the laminated portion of Vc,
most labeled neurons were in the superficial zone, and smaller numbers in
the magnocellular zone. The transganglionically labeled terminal area from
the lingual nerve overlapped mostly and that from the chorda tympani and
inferior alveolar nerve partly and that from the mental nerve rarely with
the NADPH-d neurons in Vo and Sn. In the dorsomedial paraV and Vc, the
terminal area from the lingual nerve overlapped mostly, from the inferior
alveolar and mental nerves partly and from the chorda tympani with NADPH-d
neurons. In Vo and Sn, the numbers of NADPH-d neurons decreased
statistically in the side of transected lingual nerve (P<0.02) and chorda
tympani (P<0.06). In the contralateral sides, there were no statistically
significant differences between the value of control and each
contralaterally affected nerve. In the paraV and Vc complex, the number
decreased (P<0.06) in the side of transected lingual, alveolar and mental
nerves, respectively. The number in the all contralateral sides decreased
significantly (P<0.06).
 Our present results showed that the NO/cGMP system in the trigeminal and
Sn could function for central processing of intra- and perioral structures
and be differently regulated according to each nucleus.
#Last_modified 97.03.31-22:10
#Return_path iwase@dent.osaka-u.ac.jp
#Sequence_number   85
##End

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